Studies on Tetanus Toxin and Toxoid IV. Interaction of Formaldehyde with Tetanus Toxin
نویسندگان
چکیده
منابع مشابه
Immunological studies on tetanus toxoid
T toxoid is one of the most successful vaccines used in immunization programme almost all over the world. Neonatal tetanus can be prevented by immunizing women of childbearing age with tetanus toxoid, either during pregnancy or outside of pregnancy. Tetanus vaccine is used either in mono or in combination with other antigens i.e. Diphtheria, Pertussis (whole cell or acellular), Hepatitis B, Hae...
متن کاملStudies on Tetanus Toxoid: III. Antitoxic Response in Guinea Pigs Immunized with Tetanus Alum-precipitated Toxoid Followed by Tetanus Spores.
When an individual has been given one or more injections of tetanus toxoid and, at a later date, is injured and possibly infected with Clostridium tetani, what further precautions should be taken: (1) Administer antitoxin? (2) Give another injection of tetanus toxoid to accelerate the production of antitoxin? (3) Give no further treatment, depending on his present immunity to take care of the i...
متن کاملThe Effect of Cysteine on Tetanus Toxin *
In the course of some experiments with tetanus toxin it was noted that cysteine, when added to the toxin with the intention of preserving it from oxidation, had, on the contrary, a deleterious effect. Other experiments showed that on diphtheria toxin there was but little effect, and on botulinus toxin and on ricin none at all. Locke and Maint have mentioned that cysteine can play a role in toxi...
متن کاملStructure of Tetanus Toxin DEMONSTRATION AND SEPARATION OF A SPECIFIC ENZYME CONVERTING INTRACELLULAR TETANUS TOXIN
Protease activity has been demonstrated in culture supernatants of Clostridium tetani at various stages of fermentation. Gel chromatography of the concentrated filtrates revealed the presence of three enzymatically active fractions eluting at separate positions off the column. The smallest protease was found to “nick” the single chain intracellular tetanus toxin, producing the extracellular, tw...
متن کاملImmunization with Tetanus Toxoid
Although immunization with tetanus toxoid cannot be expected to produce an adequate permanent immunity, a number of investigators have confirmed and extended the observation of Ramon3 to the effect that an organism, once immunized, will respond to further injections of toxoid with an accelerated and increased antitoxin production. That this response to the "injection de rappel" does occur has b...
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ژورنال
عنوان ژورنال: Australian Journal of Biological Sciences
سال: 1969
ISSN: 0004-9417
DOI: 10.1071/bi9691217